The Gut Microbiome - Source of Sepsis and Novel Target in Intensive Care Units?
Recruiting
Observational Study
Critical Illness
Intensive Care Unit Delirium
Neurocognitive Deficit
Microbiome,immune Function, Critically Ill
Infection in ICU
Sepsis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 100 (estimated)
- Sponsor
- Jena University Hospital · Other
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About This Trial
Here, the investigators propose to study host responses to reduced microbiome complexity driven by treatment with broad spectrum antibiotics in patients with severe infections or sepsis. The proposal aims to combine holistic approaches with emerging experimental technologies to investigate the complex interactions between the gut microbiota and its host and assess the impact of specific bacterial …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age ≥ 18 years
* One of the following criteria
1. Critically ill patients treated with meropenem or piperacillin/tazobactam started within the last 72 h
2. Critically ill patients without systemic antimicrobial therapy within the last 72 hours and an expected ICU length o…
Contacts