Evaluation of Blood Protein O-GlcNAcylation Levels in Children

Recruiting Observational Study
Sepsis Septic Shock Development and Health Metabolism Changes
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
Up to 17
Sex
Any
Study type
Observational
Participants needed
240 (estimated)
Sponsor
Nantes University Hospital · Other
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About This Trial
Stimulation of O-GlcNAcylation has been shown to be beneficial in several acute pathologies and different animal models, such as haemorrhagic and septic shock, and ischaemia-reperfusion (cerebral and cardiac). It could therefore be interesting to use this approach in children in order to limit the impact of various pathologies inducing SIRS, such as extracorporeal circulation for major surgery, se…
Trial Locations
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Eligibility Criteria
1. Healthy group Inclusion Criteria : * Age from 0 to 17 years at the time of sampling (including premature infants) * Children coming to hospital for a blood sample to be taken as part of a pre-operative check-up, an allergy check-up or a check-up as part of a pathology other than sepsis.…
Contacts

Manon Denis, MD

+33 2 40 08 34 83

manon.denis-med@chu-nantes.fr

CONTACT