The Role of Toll-like Receptor-4 in Periodontitis Patients With End-stage Renal Disease in a Sample of Egyptian Population
Recruiting
Observational Study
Periodontitis
End-stage Renal Disease
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 30 – 60
- Sex
- Any
- Study type
- Observational
- Participants needed
- 100 (estimated)
- Sponsor
- Ain Shams University · Other
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About This Trial
Chronic kidney disease (CKD) is a significant public health issue in Egypt, leading to end-stage renal disease (ESRD). ESRD patients often suffer from oral abnormalities due to the disease and medications. Periodontitis is linked to systemic diseases, including renal disease, with inflammation playing a key role. TLR4 genetic variations may influence susceptibility to CKD and periodontitis. This s…
Trial Locations
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Eligibility Criteria
Group I: Healthy Subjects with Periodontitis
Inclusion Criteria:
Age: 30 to 60 years
Gender: Both male and female
Diagnosed with Periodontitis stage II and/or stage III
Systemically healthy, no history of systemic diseases
Not on long-term medications
Exclusion Criteria:
Smokers
Individuals…
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