Lf-rTMS Attenuates Visceral Pain in Irritable Bowel Syndrome With Diarrhea

Recruiting N/A Interventional Study
Repetitive Transcranial Magnetic Stimulation Chronic Visceral Pain Functional Magnetic Resonance Imaging IBS (Irritable Bowel Syndrome) Clinical Efficacy
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 75
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
42 (estimated)
Sponsor
The First Affiliated Hospital of Soochow University · Other
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About This Trial
Objectives: To identify a central hub of visceral pain in IBS-D and elucidate the mechanism by which repetitive transcranial magnetic stimulation (rTMS) confers analgesic effects. Methods: A total of 42 IBS-D patients were recruited and randomly assigned (1:1) to the sham rTMS or the rTMS group. A nested cohort of 21 IBS-D participants who completed baseline fMRI assessments prior to randomizatio…
Trial Locations
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Eligibility Criteria
All diagnoses were made by board-certified gastroenterologists. Eligible participants met the following inclusion criteria: (1) age between 18 and 75 years; (2) fulfillment of the Rome IV diagnostic criteria for IBS-D. Exclusion criteria included: (1) presence of inflammatory or other organic gastro…
Contacts

Ruixia Weng, Dr.

15206214921

wengruixia@suda.edu.cn

CONTACT