Safety and Efficacy of Preoperative SBRT and Radical Surgery for Soft Tissue Sarcoma of Extremities

Recruiting N/A Interventional Study
Soft Tissue Sarcoma Stereotactic Body Radiotherapy Surgery
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 80
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
20 (estimated)
Sponsor
Second Affiliated Hospital, Zhejiang University, School of Medicine · Other
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About This Trial
Currently, the effectiveness and safety of preoperative hypo-fractionated radiotherapy in treating extremity soft tissue sarcomas remain inconclusive, warranting further investigation. Optimizing the neoadjuvant radiotherapy approach, including fractionation schedules and the interval between radiotherapy and surgery, is crucial to enhancing clinical efficacy while ensuring safety. This study prop…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Aged ≥18 years; 2. Confirmed diagnosis of soft tissue sarcomas; 3. Highly malignant soft tissue sarcomas; 4. Not received surgery, chemotherapy or other antitumor therapy; 5. ECOG (Eastern Cooperative Oncology Group) performance status 0 or 1; 6. Signed informed consent; 7. W…
Contacts

Haiyan Chen, MD/PhD

+8657187783521

chenhaiyan@zju.edu.cn

CONTACT