Thermotherapy for Advanced Head and Neck Cancer
Thermoradiotherapy for Locally Advanced Head and Neck Cancer Patients
Recruiting
Phase 1
Interventional Study
Head and Neck Cancer
Oropharyngeal Carcinoma
Hypopharyngeal Carcinoma
Laryngeal Cancer
Head and Neck Squamous Cell Carcinoma
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 1
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 30 (estimated)
- Sponsor
- Erasmus Medical Center · Other
Who this trial is looking for
This trial is looking for adults with advanced head and neck cancer who cannot receive chemotherapy. Participants will receive a new type of heat treatment along with their regular radiation therapy to see if it helps without causing extra side effects.
Are You a Good Fit for This Trial?
You may be able to join if
- I am at least 18 years old.
- I have advanced head and neck cancer.
- I cannot receive chemotherapy.
- I can open my mouth at least 40 mm (women) or 45 mm (men).
- I can understand the study requirements and give consent.
- I have a confirmed diagnosis of squamous cell carcinoma.
- I am able to provide written consent.
You may not be able to join if
- I have had radiation treatment on the same area before.
- I have a pacemaker or large metal markers in my body.
- I have a tracheostomy affecting the tumor location.
- I cannot position myself properly for the treatment.
- I cannot follow the follow-up schedule.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
Patients with head and neck cancer treated with radiotherapy (RT) have a substantial change of recurrence of the tumor in the pharynx or lymph nodes in the neck. Once tumor and/or lymph nodes have recurred, the prognosis is poor. To increase the efficacy of RT, usually chemotherapy is added to the treatment. However, due to age or co-morbidity chemotherapy is not always feasible to give in all pat…
Trial Locations
Loading…
Loading trial locations…
Eligibility Criteria
Inclusion Criteria:
* Age \>= 18 years
* WHO 0-1
* Mouth opening before treatment of \>= 40 mm for women and \>= 45mm for men
* Squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx, and larynx proven by cytology / histology.
* Locally advanced disease (stage III-IV).
* Curative inten…
Contacts