COMT and OPRM1 Polymorphisms and Their Effect on Post-Operative Pain in Children
Recruiting
Observational Study
Pain
Genetic Change
Children, Only
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 8 – 18
- Sex
- Any
- Study type
- Observational
- Participants needed
- 200 (estimated)
- Sponsor
- American University of Beirut Medical Center · Other
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About This Trial
The goal of this observational study is to investigate whether the A118G single-nucleotide polymorphism (SNP) in the mu-opioid receptor1(OPRM1) and Catechol-O-methyltransferase (COMT) SNPs influence postoperative pain scores in children between the ages of 8 and 18 undergoing orthopedic, abdominal, thoracic, and plastic surgeries.
The main question\[s\] it aims to answer \[is\]:
Do OPRM1 and COM…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* All children 8 years to 18 years
* Undergoing orthopedic, abdominal, thoracic, and plastic surgeries
* American Society of Anesthesiologists classification (ASA) I-II-III
Exclusion Criteria:
* Children with schizoid personality disorders, phobias, and anxiety
* Patients with…
Contacts