Genetic Study for Liver and Bile Duct Cancer

Familial Intrahepatic Cholestasis-related Genes Associated with Disease Susceptibility in Hepato-biliary Cancers

Recruiting Observational Study
Hepatobiliary Cancers Progressive Familial Intrahepatic Cholestasis (PFIC) Cholestatic Liver Disease
No Study Drug Researchers observe your health over time — no experimental treatment is given.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
12 Months and older
Sex
Any
Study type
Observational
Participants needed
600 (estimated)
Sponsor
IRCCS Azienda Ospedaliero-Universitaria di Bologna · Other
Who this trial is looking for

This trial is looking for people who have liver or bile duct cancer. Participants will provide tissue samples for research on genetic factors related to cholestatic liver diseases and cancer.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have been diagnosed with liver or bile duct cancer.
  • I have undergone surgery or a liver transplant for treatment.
  • I have cholestatic liver disease with specific test results.
  • I have experienced itching and high bile acid levels for over 6 months.
  • I am willing to sign a consent form.

You may not be able to join if

  • I have another known cause of chronic liver disease.
  • I have primary biliary cholangitis.
  • I have primary sclerosing cholangitis.
  • I have IgG4-related cholangiopathy.
  • I have obstructive jaundice.
  • I have tested positive for hepatitis B, C, or E.
  • I have a history of alcohol abuse.
  • I have hemochromatosis.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer a few quick questions to see if you may meet the eligibility requirements.

Check Your Eligibility
About This Trial

This is a cross-sectional, multicenter tissue study with an exploratory aim to estimate the prevalence of genetic mutations that predispose individuals to diseases in the context of cholestatic disorders and hepatobiliary neoplasms. It is intended as a hypothesis-generating study for future empirical investigations.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Instrumental or histological diagnosis of HBCs, defined as primary liver and/or biliary tumors (hepatocellular carcinoma, cholangiocarcinoma, hepatocholangiocarcinoma) occurring in patients without apparent underlying chronic liver disease or in the context of cryptogenic chro…
Contacts

Giovanni Vitale

051.214.3702

giovanni.vitale@aosp.bo.it

CONTACT