STI Prophylaxis and Emergence of Antimicrobial Resistance
Recruiting
Observational Study
Sexually Transmitted Infection (STI) Prevention
Antibiotic Prophylaxis
Antibiotic Resistance, Bacterial
Microbiome
Doxycycline
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Male
- Study type
- Observational
- Participants needed
- 108 (estimated)
- Sponsor
- University College, London · Other
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About This Trial
The goal of this observational study is to understand the risk of antibiotic resistance and changes in the human microbiome (bacteria that live inside and on us), if people use antibiotics to prevent sexually transmitted infections (STI prophylaxis, doxycycline post-exposure prophylaxis, or 'doxyPEP'). The study will assess how easy and acceptable it is to find antibiotic resistance and microbiome…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Aged ≥ 18 years.
* Identifies as a man (cis or trans).
* Has sex with men.
* Able to provide informed consent.
Exclusion Criteria:
* Use of an antibiotic other than doxycycline in the 3 months prior to enrolment
* Currently being treated for an STI with doxycycline
* Use of …
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