Randomized Controlled Multicenter Study Comparing Steroid Therapy Plus Anticoagulants to Steroid Therapy Alone in Deep Venous Thrombosis of Behçet's Syndrome

Recruiting Phase 3 Interventional Study
Behcet Syndrome
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 3
Study type
Interventional
Purpose
Treatment
Participants needed
134 (estimated)
Sponsor
Assistance Publique - Hôpitaux de Paris · Other
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About This Trial
In patients with Behçet's syndrome (BS), deep venous thrombosis (DVT) is thought to result from inflammation of the vessel wall rather than hyper coagulability. Post Thrombotic Syndrome (PTS) is frequent especially with recurrent episodes of deep vein thrombosis and may result in leg ulcers that are very difficult to treat. Vascular involvement is a major cause of morbidity and mortality among BS…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Age ≥ 18 years old 2. Diagnosis of BS according to the international criteria 3. First or recurrent deep venous thrombosis diagnosed on imaging (venous ultrasonography , and/or Angio CT scan and/or angio MRI) 4. Written inform consent 5. Women of childbearing potential (WOCBP…
Contacts

David Saadoun, MD PhD

0142178042

david.saadoun@psl.aphp.fr

CONTACT

Jérôme Lambert, MD PhD

0142499742

jerome.lambert@u-paris.fr

CONTACT