Mesenchymal Stem Cells for Alzheimer's Disease Behavior Issues

Human Mesenchymal Stem Cells (hMSC) in Behavioral Problems Due to Alzheimer's Disease.

Recruiting Phase 2 Interventional Study
Alzheimer Disease Agitation in Dementia
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
55 – 90
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
8 (estimated)
Sponsor
Bernard (Barry) Baumel · Other
Who this trial is looking for

This trial is looking for adults with moderate to severe Alzheimer's disease who have behavioral problems. Participants will receive one infusion of stem cells along with their current medication for behavior control.

Are You a Good Fit for This Trial?
Must be taking Antipsychotic medication

You may be able to join if

  • I am between 55 and 90 years old.
  • I have been diagnosed with probable Alzheimer's disease.
  • I have had brain imaging that shows signs of Alzheimer's disease.
  • I have behavioral symptoms like agitation or hallucinations.
  • My behavioral symptoms started at least 4 weeks before screening.
  • I have been taking antipsychotic medication for at least 4 weeks.
  • I have a family member or friend who can answer questions about me.

You may not be able to join if

  • I have dementia other than Alzheimer's disease.
  • I have severe depression.
  • I have a recent history of substance abuse.
  • I have a bleeding disorder or certain viral infections.
  • I have had cancer in the past 3 years, except for some treated skin cancers.
  • I have uncontrolled medical conditions like hypertension or diabetes.
  • I have received experimental treatments for Alzheimer's disease recently.
  • I am premenopausal.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

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About This Trial

The purpose of this research study is to test if adding one infusion of mesenchymal stem cells to the current treatment with antipsychotic medication may help control behavioral problems in people with a diagnosis of moderate to severe Alzheimer's disease.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Adults 55-90 years at the time of signing consent * A diagnosis of probable Alzheimer disease (AD), defined by the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders Association (NINCDS-ADRDA) criteria * …
Contacts

Bernard Baumel, MD

(305) 243-3100

mep980@miami.edu

CONTACT