"The Effect of Inhaled Nitroglycerin for COPD Patients

Recruiting Phase 2 Phase 3 Interventional Study
COPD COPD III/IV
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2/3
Study type
Interventional
Purpose
Treatment
Participants needed
40 (estimated)
Sponsor
Beni-Suef University · Other
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About This Trial

this study aims to investigative the benefits of using nebulized nitroglycerin in improving respiratory functions in patients of late stage COPD

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Adult patient's ≥ 18 years old COPD exacerbation with respiratory failure and Echo evidenced presence of pulmonary hypertension (defined as mean pulmonary artery pressure \> 20 mmHg) Exclusion Criteria: * Profound left ventricular failure, as the decrease in pulmonary vascul…
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