Selecting Hypoxic Tumours for Treatment Modification
Recruiting
Observational Study
Bladder (Urothelial, Transitional Cell) Cancer
Prostate Cancer
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 30 (estimated)
- Sponsor
- University of Manchester · Other
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About This Trial
Approximately 50% of cancer patients with solid tumours will be treated with radiotherapy. A significant proportion (\>25%) of patients have hypoxic tumours which respond poorly to radiotherapy. Hypoxic tumours have a poor prognosis. This can be improved with treatment intensification. Treatment intensification can be modification with CON (breathing O2-enriched air + oral administration of nicoti…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
This will be tumour site dependent.
Bladder:
* Older than age 18 years.
* Patients having radiotherapy at the Christie NHS Foundation Trust suitable for imaging on an MRI scanner.
* Able to give informed consent.
Cervix:
* Older than age 18 years.
* Patients having radiother…
Contacts