No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 85
Sex
Any
Study type
Interventional
Purpose
Supportive Care
Participants needed
147 (estimated)
Sponsor
Mayo Clinic · Other
Who this trial is looking for
This trial is looking for patients with multiple sclerosis or certain types of cancer, along with their caregivers, to see how breathing exercises might help their brain and mental health. Participants will need to perform light exercise and use a smartphone or tablet.
Are You a Good Fit for This Trial?
You may be able to join if
I can perform light exercise
I have multiple sclerosis or specific types of cancer
I can read and understand English
I have access to a smartphone or tablet
You may not be able to join if
I cannot undergo an MRI due to a pacemaker or metal implants
I have chronic medical conditions like heart disease or COPD
I have psychiatric conditions like psychosis or major depression
I am pregnant or planning to become pregnant during the study period
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
This clinical trial studies the effect of respiratory training for enhancing brain and mental health among patients with multiple sclerosis (MS) and cancer (along with their caregivers). The relationship between respiration, cardiovascular effects in the brain, mental health, and neurophysiological mechanisms are significant for patient populations facing complex health challenges, such as those w…
This clinical trial studies the effect of respiratory training for enhancing brain and mental health among patients with multiple sclerosis (MS) and cancer (along with their caregivers). The relationship between respiration, cardiovascular effects in the brain, mental health, and neurophysiological mechanisms are significant for patient populations facing complex health challenges, such as those with cancer and neurodegenerative disease, and their caregivers. By measuring oxygen delivery to brain tissues and cerebrospinal fluid flow, this trial may help researchers investigate the potential benefits of respiratory training for patients with MS and cancer and their caregivers.
Trial Locations
Loading…
Loading trial locations…
Facility
City
State
Country
Status
Eligibility Criteria
Inclusion Criteria:
* STUDY 1: Participants must be physically fit enough to perform light exercise.
* STUDY 1: Should read and understand English well enough to consent, complete measures, and follow instructions.
* STUDY 1: Must have access to a smartphone or tablet.
* STUDY 2: Participants must …
Inclusion Criteria:
* STUDY 1: Participants must be physically fit enough to perform light exercise.
* STUDY 1: Should read and understand English well enough to consent, complete measures, and follow instructions.
* STUDY 1: Must have access to a smartphone or tablet.
* STUDY 2: Participants must be physically fit enough to perform light exercise.
* STUDY 2: Cancer patients may have prostate cancer, neuroendocrine tumor, or brain cancer in any stage.
* STUDY 2: The main focus is on pairs of cancer patients and their respective caregivers, but individual cancer patients or individual caregivers are also acceptable.
* STUDY 2: Participants should read and understand English well enough to consent, complete measures, and follow instructions.
* STUDY 2: They also must have access to a smartphone or tablet.
* STUDY 3: Participants must be physically fit enough to perform light exercise.
* STUDY 3: The patient should have multiple sclerosis.
* STUDY 3: Participants should read and understand English well enough to consent, complete measures, and follow instructions.
* STUDY 3: They also must have access to a smartphone or tablet.
Exclusion Criteria:
* STUDY 1: Participants incompatible with MRI machines due to factors such as pacemakers or metallic implants.
* STUDY 1: Additionally, those with chronic medical conditions, including heart disease (coronary artery disease, congestive heart failure, hypertension, cardiac arrhythmia), chronic obstructive pulmonary disease (COPD), cystic fibrosis, cancer, diabetes, sleep apnea, aneurysms, and neurological conditions (epilepsy, Alzheimer's disease, Huntington' disease, essential tremor and Parkinson disease) are excluded.
* STUDY 1: Participants with psychiatric conditions such as psychosis, suicidality, bipolar disorder, major depression, and substance use disorders are excluded.
* STUDY 1: Participants serving as caregivers for any of the aforementioned conditions and for other illnesses such as cancer or neurological disorders, are also excluded.
* STUDY 1: Further exclusions apply to those with severe vision, hearing impairments, have a body mass index (BMI) over 30, and those who are pregnant.
* STUDY 1: Those planning to become pregnant during the study period will be excluded.
* STUDY 2: Participants incompatible with MRI machines due to factors such as pacemakers or metallic implants are excluded, as are those with chronic lung disease (chronic obstructive pulmonary disease \[COPD\], cystic fibrosis), aneurysms, and those who are pregnant.
* STUDY 2: Those planning to become pregnant during the study period will be excluded.
* STUDY 3: Participants incompatible with MRI machines due to factors such as pacemakers or metallic implants are excluded, as are those with chronic lung disease (chronic obstructive pulmonary disease \[COPD\], cystic fibrosis), aneurysms, and those who are pregnant.
* STUDY 3: Those planning to become pregnant during the study period will be excluded.
Picking one helps us show the most relevant trials first.
Your results are loading in the background — you can
change this any time from the results page.
Set your location to continue
Find My Trials uses your location to surface clinical trials near you.
Add your city or zip code to your profile and try again.