A Study Investigating Oral Semaglutide in People with Open-Angle Glaucoma
Recruiting
Phase 4
Interventional Study
Primary Open Angle Glaucoma (POAG)
Open-Angle Glaucoma
Glaucoma
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 45 and older
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 126 (estimated)
- Sponsor
- Glostrup University Hospital, Copenhagen · Other
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About This Trial
The aim of this clinical trial is to investigate whether oral semaglutide can be used to treat open-angle glaucoma. The main question it aims to answer is: Does oral semaglutide safely improve inner retinal function in patients with open-angle glaucoma as measured by the photopic negative response of the electroretinogram.
Researchers will compare oral semaglutide to a placebo (a look-alike subst…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Ability to read and speak Danish
* 45 years or older at the time of inclusion
* Visual acuity equal to or above 0.5 in the study eye
* Diagnosis of POAG with MD ≤ 16 dB with repeatable and reliable (false positive less than 15 %) VF loss measured by standard automated perimetr…
Contacts