Letrozole for Ovulation in Women with PCOS

Comparative Study Between HOMA1-IR and HOMA2-IR in Prediction of Ovulation Outcome in Women With PCOS

Recruiting N/A Interventional Study
Polycystic Ovarian Syndrome (PCOS)
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 35
Sex
Female
Study type
Interventional
Purpose
Diagnostic
Participants needed
122 (estimated)
Sponsor
Cairo University · Other
Who this trial is looking for

This trial is looking for women with Polycystic Ovarian Syndrome (PCOS) who want to get pregnant. Participants will take a medication called Letrozole and have regular check-ups to monitor their ovulation.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am aged between 18 and 35 years old.
  • I have been trying to get pregnant for 1 to 4 years.
  • I have been diagnosed with Polycystic Ovarian Syndrome (PCOS).

You may not be able to join if

  • I have infertility due to other factors like tubal issues.
  • I have endometriosis.
  • I have ovarian cysts.
  • I have hormonal disorders like diabetes or thyroid problems.
  • I have a history of poor ovarian response.
  • I have chronic diseases or autoimmune conditions.
  • I have issues with my blood that could affect pregnancy.
  • I have contraindications to pregnancy.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer a few quick questions to see if you may meet the eligibility requirements.

Check Your Eligibility
About This Trial
122 women diagnosed with PCOS seeking fertility in the fertility clinic at kasr Alainy hospital will be subjected to Homeostatic model assessment for insulin resistance 1 was calculated for all participants through the equation \[glucose (mmol/L) × insulin (µU/L)\]/22.5 while homeostatic model assessment for insulin resistance 2 was calculated by the HOMA2 calculator. All women will be subjected t…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age 18-35 years * duration of infertility 1-4 years * PCOS Exclusion Criteria: women with other causes of infertility (tubal factor assessed by laparoscopy or hysterosalpingogram, uterine cavity abnormality assessed by ultrasound or hysteroscopy or male factor assessed by se…
Contacts

Ahmed Maged, MD

01005227404

dr_ahmedmaged08@kasralainy.edu.eg

CONTACT

Ahmed Chamel, MD

+20 110 066 2255

ahmed-chamel@hotmail.com

CONTACT