PET Imaging of Phosphodiesterase-4B (PDE4B) in Alcohol Use Disorder
Recruiting
Phase 1
Interventional Study
Alcohol Use Disorder
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 70
- Sex
- Any
- Trial phase
- Phase 1
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 30 (estimated)
- Sponsor
- National Institute of Mental Health (NIMH) · NIH
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About This Trial
Background:
People with alcohol use disorder (AUD) also often have bouts of depression called major depressive episodes (MDEs). People having MDEs have been found to have low levels of a protein called PDE4B in the brain. Researchers want to find out if people with AUD also have low levels of PDE4B. This research may help lead to better treatments for AUD.
Objective:
To find out (1) if PDE4B le…
Trial Locations
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Eligibility Criteria
* INCLUSION CRITERIA:
1. Age 18-70 years
2. Willingness to complete the study including MRI tests.
3. Each participant must have a level of understanding sufficient to agree to all required tests and examinations and sign an informed consent document.
4. Participants must have their radial …
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