Insights Into the Pathophysiology of Neurovascular Uncoupling in Patients with Brain Lesions.
Recruiting
N/A
Interventional Study
Glioblastoma
Glioma
Astrocytoma
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 90
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 40 (estimated)
- Sponsor
- Erasme University Hospital · Other
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About This Trial
Neurovascular uncoupling (NVU) represents a major source of potential bias for the identification of eloquent brain regions through activation procedures in blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI).
Same region shows proper pattern in glucose metabolism in victiny of brain lesions, investigated with positron emitted tomography with radiolabeled glucose (PET…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* patients in the study include prior imaging showing a potentially resectable intra-cerebral mass lesion. Patient has to be included before surgery, chemotherapy and radiation
Exclusion Criteria:
* previous brain surgery
* respiratory failure
* Asthma
* Claustrophobia
* Previ…
Contacts