First-in-human Integrated Endoscopic Ultrasound (EUS) Navigation System Clinical Study

Inclusion Criteria: * Man or woman over the age of 18 years old. * Patient having a EUS procedure for pancreas study planned within the frame of his or her clinical care. * Patient whom pre-operative imaging indicates one lesion, a suspicion of lesion, chronic pancreatitis or fatty pancreas. * Patient with a good definition on the CT scan done within the year to the EUS. * Patient able to receive and understand information related to the study and give his or her written consent. * Patient affiliated to the French social security system. Exclusion Criteria: * Patient with altered anatomy of the upper digestive tract due to previous surgery. * Patient with known abnormal anatomy of the upper digestive tract. * Patient wearing a pacemaker. * Patients with comorbidities that may increase the risk of perforation. * Patient presenting, according to the investigator's judgment, a disease which may prevent participation in the procedures provided for by the study. * Patient with an ASA \>3. Patient with ASA=3 must be validated by the Principal * Investigator (PI). * Patient unable to tolerate general anesthesia. * Patient with a body mass index (BMI) \< 18,5 and \> 40. * Patient with weight variations \>10% between the date on which the CT scan was performed and the date of the procedure. * Pregnant or lactating patient. * Patient in exclusion period (determined by a previous or a current study). * Patient under guardianship or trusteeship. * Patient under the protection of justice of deprives of liberty. * Patient in situation of emergency Perprocedure exclusion criteria • Patient in need of the balloon during the navigation will be excluded of the study (Experimental group)