Adrenaline Nasal Pack vs Xylometazoline Nasal Drops During Nasotracheal Intubation
Recruiting
Phase 2Phase 3Interventional Study
Nasal BleedingNasotracheal Intubation
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Pivotal Trial
This treatment is in the last trial phase before FDA approval.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 60
Sex
Any
Trial phase
Phase 2/3
Study type
Interventional
Purpose
Prevention
Participants needed
70 (estimated)
Sponsor
Shaheed Mohtarma Benazir Bhutto Institue of Trauma · Other
Who this trial is looking for
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Answer a few quick questions to see if you may meet the eligibility requirements.
The goal of this trial is to compare efficacy of xylometazoline nasal drops and adrenaline nasal pack in participants undergoing elective oromaxillofacial surgeries.
The main question aim to answer is xylometazoline nasal drops better than adrenaline nasal packing in terms of nasal bleeding during nasotracheal intubation. Researchers are comparing 2 groups of participants.
Participants in group …
The goal of this trial is to compare efficacy of xylometazoline nasal drops and adrenaline nasal pack in participants undergoing elective oromaxillofacial surgeries.
The main question aim to answer is xylometazoline nasal drops better than adrenaline nasal packing in terms of nasal bleeding during nasotracheal intubation. Researchers are comparing 2 groups of participants.
Participants in group Xylometazoline are receiving 0.1% xylometaxoline nasal drops.
Participants in group Adrenaline are receiving adrenaline nasal packing.
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
* ASA 1 and 2
* Age group between 18-60 years
* Mallampati score 1 and 2
* Either gender
* Participants who undergo elective oromaxillofacial surgery
Exclusion Criteria:
* Lack of consent
* Participants with anticipated difficult airway
* Participants receiving anticoagulant t…
Inclusion Criteria:
* ASA 1 and 2
* Age group between 18-60 years
* Mallampati score 1 and 2
* Either gender
* Participants who undergo elective oromaxillofacial surgery
Exclusion Criteria:
* Lack of consent
* Participants with anticipated difficult airway
* Participants receiving anticoagulant therapy
* History of nasal abnormality (nasal surgery, trauma, polyp, obstruction)
* History of repeated epistaxis
* History of uncontrolled hypertension, diabetes, pregnancy, and any other cardiac or cerebral events.
Contacts
Dr Sidra Javed Consultant Anaesthetist, MBBS, FCPS, PAIN FELLOW
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