Pilot Trial of Colchicine for Graft Failure in CABG
Recruiting
Phase 4
Interventional Study
CABG
Graft Failure
Colchicine
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 100 (estimated)
- Sponsor
- Ruijin Hospital · Other
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About This Trial
The goal of this pilot trial is to to evaluate the preliminary effect of oral colchicine therapy on graft outcomes in patients underwent primary isolated CABG.
The main questions it aims to answer is:
1. Whether the oral colchicine therapy may reduce the failure outcome of grafts after CABG.
2. Whether it is feasible to construct a muticenter powered trial to test the superiority hypothesis.
Re…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age≥18 years old，
* Any sex，
* Signed informed consent，
* Within 3 days after a successful isolated CABG
Exclusion Criteria:
* Allergy,
* Hematopoietic dysfunction,
* Moderate to severe hepatic dysfunction,
* Moderate to severe renal dysfunction.
Contacts