Systemic and Tumor Immune Response During Pelvic (Chemo)Radiation and/or Brachytherapy for Cervical Cancer
Recruiting
Observational Study
Cervical Carcinoma
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Female
- Study type
- Observational
- Participants needed
- 110 (estimated)
- Sponsor
- Tata Memorial Hospital · Government
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About This Trial
Radiotherapy result in tumor cell death by creating an immune potentiation effect, but can also lead to long lasting immune suppression. Thus the investigators hypothesize that pelvic and/or para-aortic radiotherapy for cervical cancer affects local tumor immunity as well as systemic immune response that may be instrumental for long term cancer cure. The goal of this observational study is to unde…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Common Inclusion Criteria:
1. Age 18 years and above.
2. Ability to tolerate full course of pelvic radiotherapy+/- chemotherapy +/- brachytherapy.
3. Ability to understand and willingness to sign an informed consent document.
4. Should be willing to undergo extra biop…
Contacts