Left Ventricular Reverse Remodeling Evaluation After Surgical Correction of Aortic Regurgitation
Recruiting
Observational Study
Aortic Valve Regurgitation
Mitral Valve Regurgitation
Left Ventricle Dilated
Left Atrium Dilated
Systolic Left Ventricular Heart Failure
Diastolic Heart Failure
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 120 (estimated)
- Sponsor
- Petrovsky National Research Centre of Surgery · Other
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About This Trial
Investigators assume that surgical correction approach to functional mitral regurgitation during intervention for chronic aortic regurgitation in patients with severe enlargement of the left heart chambers influences reverse remodeling of the left ventricle (LV) in the postoperative period. It is suggested that functional mitral regurgitation (MR) provides supra-physiological left ventricle volume…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age over 18 years
* Planned primary elective surgery for chronic aortic regurgitation
* Presence of functional mitral regurgitation
* End-diastolic volume of the left ventricle \>= 250 ml
Exclusion Criteria:
* Infectious endocarditis
* History of myocardial infarction
* I…
Contacts