Human Leukocyte Antigen (HLA) Mismatched Unrelated Allogeneic Hematopoietic Stem Cell Transplantation

Recruiting Phase 1 Interventional Study
Hematologic Disease
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 60
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Treatment
Participants needed
29 (estimated)
Sponsor
He Huang · Other
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About This Trial
This study is a single center, prospective, single arm exploratory clinical trial that includes patients with hematological malignancies who are indicated for allogeneic hematopoietic stem cell transplantation (allo HSCT) but lack suitable donors. This project plans to use highly mismatched unrelated HLA mismatched donors. Ultimately, an unrelated human leukocyte antigen (HLA) mismatched allo HSCT…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Adult patients (18-60 years old) with hematological malignancies and indications for hematopoietic stem cell transplantation; * Non blood donors without human leukocyte antigen (HLA) high-resolution typing ≥ 9/10, or those who have difficulty finding non blood donors due to ur…
Contacts

Yishan Ye, MD., PhD

+8618268068056

yeyishan@hotmail.com

CONTACT