Study on Immune Aging in Sepsis Patients
Role of Transposable Elements in Septic Immune Aging
Recruiting
Observational Study
Sepsis
Sepsis and Septic Shock
Sepsis With Multiple Organ Dysfunction (MOD)
Sepsis With Acute Organ Dysfunction
Sepsis, Severe
Sepsis at Intensive Care Unit
Sepsis, Severe Sepsis and Septic Shock
Sepsis, Septic Shock
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 116 (estimated)
- Sponsor
- University of California, San Francisco · Other
Who this trial is looking for
This trial is looking for adults who are in the ICU with sepsis. Participants will have blood drawn but will not receive any other treatments for this study.
Are You a Good Fit for This Trial?
You may be able to join if
- I am 18 years or older
- I am in the ICU with sepsis
- I have a SOFA score of at least 2
You may not be able to join if
- I am on immunosuppressive medication for organ transplantation
- I have preexisting leukopenia
- I am receiving CAR-T therapy for cancer
- I am under 18 years old
- I have an ongoing bleeding issue
- My chronic hemoglobin level is below 7.0
- I rely on blood transfusions
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
The goal of this observational study is to learn about how transposable element levels affect the patient outcomes in sepsis. The main questions it aims to answer is:
1. Do transposable elements prematurely age the immune systems of patients with sepsis?
2. Do transposable elements correlate with increased mortality in patients with sepsis in the ICU?
3. Do transposable elements correlate with in…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age 18 or older
* Admitted to ICU with sepsis (Sepsis 3 Criteria)
* SOFA score of at least 2 at time of enrollment
Exclusion Criteria:
* Patients on organ transplantation immunosuppression
* Patients with preexisting leukopenia
* Cancer patients receiving CAR-T therapy
* Pat…
Contacts