Two-cycle and Three-cycle Induction Therapy With Modified TPF Regimen Combined and Camrelizumab for LANPC

Recruiting Phase 2 Interventional Study
Nasopharyngeal Neoplasms PD-1 Inhibitor Induction Therapy Complete Response Chemotherapy
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 – 65
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
208 (estimated)
Sponsor
The First Affiliated Hospital of Xiamen University · Other
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About This Trial

This prospective, phase II, multicenter, randomized controlled study aims to compare the complete response rate and long-term survival outcomes of two-cycle and three-cycle induction therapy with modified TPF regimens combined with camrelizumab in patients with locally advanced nasopharyngeal carcinoma.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age: 18-65 years old; * Pathologically (including histology or cytology) confirmed nasopharyngeal carcinoma patients, with clinical staging T1-4N2-3M0 (according to the UICC/AJCC TNM staging system, 8th edition); * No prior systemic treatment (surgery, radiotherapy, chemothera…
Contacts

San-Gang Wu, MD

865922139531

wusg@xmu.edu.cn

CONTACT