Effects of Ketone Supplement and Alcohol on Brain Metabolism

Recruiting Phase 2 Phase 3 Interventional Study
Ketosis Alcohol Drinking MRI
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
21 – 65
Sex
Any
Trial phase
Phase 2/3
Study type
Interventional
Purpose
Basic Science
Participants needed
60 (estimated)
Sponsor
University of Pennsylvania · Other
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About This Trial
The research study is being conducted to better understand the effects of ketones and alcohol on brain functioning and brain metabolism. Participants will be asked to undergo three identical MRI visits after three single-dose interventions: (1) drink a ketone supplement drink, (2) drink an alcoholic beverage, (3) no intervention. These interventions will be randomly assigned (meaning everyone rece…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Able to provide written informed consent and commit to completing study procedures. 2. Reported on at least one day in the month before consent of consuming 2 or more standard alcoholic drinks on a single day. Exclusion Criteria: 1. Unwilling or unable to refrain from the u…
Contacts

Timothy Pond, MPH

215-746-1959

timpond@Pennmedicine.upenn.edu

CONTACT