Effects of Ketone Supplement and Alcohol on Brain Metabolism
Recruiting
Phase 2
Phase 3
Interventional Study
Ketosis
Alcohol Drinking
MRI
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Pivotal Trial
This treatment is in the last trial phase before FDA approval.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 21 – 65
- Sex
- Any
- Trial phase
- Phase 2/3
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 60 (estimated)
- Sponsor
- University of Pennsylvania · Other
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About This Trial
The research study is being conducted to better understand the effects of ketones and alcohol on brain functioning and brain metabolism. Participants will be asked to undergo three identical MRI visits after three single-dose interventions: (1) drink a ketone supplement drink, (2) drink an alcoholic beverage, (3) no intervention. These interventions will be randomly assigned (meaning everyone rece…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Able to provide written informed consent and commit to completing study procedures.
2. Reported on at least one day in the month before consent of consuming 2 or more standard alcoholic drinks on a single day.
Exclusion Criteria:
1. Unwilling or unable to refrain from the u…
Contacts