Effect of Low-dose EsketaMine on dElirium in High-risk Elderly Patients uNdergoing elecTive Surgery (ELEMENT)
Recruiting
N/A
Interventional Study
Delirium in Old Age
Delirium, Postoperative
Anesthesia
Cognitive Dysfunction
Pain, Postoperative
Esketamine
Non-cardiac Surgery
At a Glance
- Age
- 65 – 90
- Sex
- Any
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 1,670 (estimated)
- Sponsor
- Nanfang Hospital, Southern Medical University · Other
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About This Trial
Delirium is an acutely occurred neurocognitive disorder characterized by fluctuating symptoms of inattention, altered consciousness and cognitive dysfunction. Delirium is reported to occur in 4% to 65% of postoperative patients depending on the population, and is especially common in older patients. Postoperative delirium is disturbing to patients and their families, and it is a strong predictor o…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age ≥65 years and \<90 years;
* Scheduled to undergo major non-cardiac surgery.
* Fulfill at least one of risk factors as follows: history of stroke; history of delirium; hypertension; congestive heart failure; coronary artery disease; atrial fibrillation; peripheral artery di…
Contacts