Study on Evaluating the Effectiveness of Statins in the Treatment of Moyamoya Disease
Recruiting
Observational Study
Moyamoya Disease
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 60
Sex
Any
Study type
Observational
Participants needed
330 (estimated)
Sponsor
Beijing Tiantan Hospital · Other
Who this trial is looking for
This trial is looking for adults diagnosed with moyamoya disease. Participants will take statins and undergo imaging tests to assess how well the treatment works.
Are You a Good Fit for This Trial?
You may be able to join if
I have been diagnosed with moyamoya disease.
I am at least 18 years old.
I have signed the informed consent form.
I have a baseline mRS score of 2 or less.
I am receiving revascularization or conservative treatment.
I have at least one imaging follow-up result.
You may not be able to join if
I have a history of stroke more than three months ago.
I am under the age of 18.
I am currently pregnant.
I have had a heart condition or recent surgery related to the heart.
I have concurrent brain or blood vessel conditions.
I am allergic to contrast media.
I am unable to undergo imaging follow-up.
I have atherosclerosis or autoimmune diseases.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
The purpose of this study is to investigate the effectiveness of statins in the treatment of moyamoya disease based on multimodal magnetic resonance imaging.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. The imaging examination meets the diagnostic criteria for moyamoya disease;
2. Sign the informed consent form;
3. Age ≥18 years old;
4. Baseline mRS score ≤2 points;
5. The patient receives revascularization/conservative treatment;
6. There is at least 1 imaging follow-up res…
Inclusion Criteria:
1. The imaging examination meets the diagnostic criteria for moyamoya disease;
2. Sign the informed consent form;
3. Age ≥18 years old;
4. Baseline mRS score ≤2 points;
5. The patient receives revascularization/conservative treatment;
6. There is at least 1 imaging follow-up result.
Exclusion Criteria:
1. Patients with atherosclerosis, autoimmune diseases, meningitis, Down syndrome, cranial trauma, or those who have undergone radioactive head irradiation, as these conditions may lead to secondary cerebrovascular disease and contribute to the development of Moyamoya syndrome;
2. Individuals under the age of 18;
3. Participants who refuse to take part in this study;
4. Pregnant patients;
5. Those with concurrent intracranial aneurysms, cerebrovascular malformations, brain tumors, or hydrocephalus;
6. A history of stroke occurring more than three months prior to the diagnosis of Moyamoya disease;
7. Individuals with a history of coronary heart disease or previous cardiovascular and cerebrovascular surgical interventions, including cerebral revascularization, intracranial artery stent implantation, carotid artery stenting, endarterectomy, coronary artery bypass grafting, or coronary stent implantation;
8. Allergies to contrast media;
9. Patients with missing imaging data or whose image quality cannot be analyzed;
10. Individuals who refuse or are unable to undergo imaging follow-up;
11. Patients receiving other types of lipid-lowering drug treatments.
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