Tranexamic Acid for Second Trimester Dilation and Evacuation and Bleeding Outcomes

Recruiting Phase 4 Interventional Study
Abortion Dilation and Evacuation Hemorrhage Prophylactic Tranexamic Acid Use Blood Loss
Prior Safety Data This treatment has already been tested in at least one earlier human trial. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
18 and older
Sex
Female
Trial phase
Phase 4
Study type
Interventional
Purpose
Prevention
Participants needed
276 (estimated)
Sponsor
University of California, San Diego · Other
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About This Trial
Although procedural abortion in the second trimester is extremely safe, hemorrhage is one of the leading causes of morbidity and mortality. Tranexamic acid (TXA) is used commonly in obstetrics to prevent or manage intrapartum or postpartum hemorrhage and has been associated with decreased mortality and decreased blood loss at the time of birth. Some guidelines are recommending the use of TXA for b…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Able to understand and sign informed consent * Speaks English or Spanish language, * Requesting pregnancy termination or procedural management of fetal demise - Intrauterine pregnancy, 18 weeks 0 days and 24 weeks and 0 days gestation Exclusion Criteria: * History of or curr…
Contacts

Karen Greiner, MD, MPH

858-329-4464

familyplanningresearch@health.ucsd.edu

CONTACT