Use of SPY Imaging System to Minimize Fistulas After Hypopharyngeal Reconstruction

Recruiting Phase 2 Interventional Study
Squamous Cell Carcinoma Pharyngocutaneous Fistula
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
225 (estimated)
Sponsor
Matthew Spector · Other
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About This Trial
Investigators performing this research want to look at the use of a special imaging process during a specific throat surgery. Using this imaging may help to lower a common complication that called a pharyngocutaneous fistula (PCF). A PCF is a leak in the tube in the throat that helps with breathing and digesting food. The imaging is called the SPY Fluorescence System. This system can identify tis…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Prior diagnosis of biopsy-proven squamous cell carcinoma of the larynx or hypopharynx (stage II-IV) 2. Prior treatment with radiation +/- chemotherapy 3. Presence of local recurrence of disease, radiation necrosis or an incompetent larynx 4. 18 years or older. 5. Ability to u…
Contacts

Matthew E Spector, MD

412-647-2100

spectorme@upmc.edu

CONTACT