Final Oocyte Maturation and Ovarian Stimulation Study
Follicular Volume at the Time of Final Oocyte Maturation in Poor Responders, and Its Correlation With Oocyte Maturity
Recruiting
Observational Study
OVARIAN STIMULATION
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 48
Sex
Female
Study type
Observational
Participants needed
100 (estimated)
Sponsor
ART Fertility Clinics LLC · Other
Who this trial is looking for
This trial is looking for women with reduced ovarian function who are undergoing procedures to collect eggs. Participants will help researchers understand how the size of the follicles affects egg quality and timing of treatment.
Are You a Good Fit for This Trial?
You may be able to join if
I am between 18 and 48 years old.
I am undergoing ovarian stimulation for egg freezing.
I am having IVF or ICSI with genetic testing.
I have 3 or fewer antral follicles at the start of stimulation.
I am in the follicular phase of my menstrual cycle.
You may not be able to join if
I have had sperm retrieved through surgery.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Women with a severely diminished ovarian reserve and monofollicular growth are at a higher risk of premature ovulation as well as poor quality oocytes. Our group showed previously that women with severely diminished ovarian reserve benefit from receiving the final oocyte maturation at smaller follicle sizes in terms of reducing the risk of premature ovulation and finding mature oocytes even out of…
Women with a severely diminished ovarian reserve and monofollicular growth are at a higher risk of premature ovulation as well as poor quality oocytes. Our group showed previously that women with severely diminished ovarian reserve benefit from receiving the final oocyte maturation at smaller follicle sizes in terms of reducing the risk of premature ovulation and finding mature oocytes even out of small size follicles.
Adding the measurement of the follicular volume at the time of final oocyte maturation might provide more information on the proper timing of trigger administration compared to the follicular size alone, hormonal profile as well as previous stimulation attempts. Setting a cutoff value of follicular volume for trigger might help to avoid premature ovulation and possibly increase the chances of ending up with a euploid embryo.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Reproductive age group: 18 -48
* undergoing ovarian stimulation for oocyte vetrification
* undergoing IVF/ ICSI with PGT-A / PGT-M / PGT- Sr
* less than or equal to 3 AFC on initiation of stimulation
* follicular phase stimulation
Exclusion Criteria:
* surgically retrieved s…
Inclusion Criteria:
* Reproductive age group: 18 -48
* undergoing ovarian stimulation for oocyte vetrification
* undergoing IVF/ ICSI with PGT-A / PGT-M / PGT- Sr
* less than or equal to 3 AFC on initiation of stimulation
* follicular phase stimulation
Exclusion Criteria:
* surgically retrieved sperm
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