Stimulating Fat Tissue Storage With Niacin to Reduce Fat Accumulation in the Liver.
Recruiting
N/A
Interventional Study
Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD)
Liver Fibrosis/NASH
Non-Alcoholic Steato-Hepatitis (NASH)
At a Glance
- Age
- 20 – 80
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 36 (estimated)
- Sponsor
- Université de Sherbrooke · Other
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About This Trial
Metabolic dysfunction-associated steatotic liver disease (MASLD) (aka non-alcoholic fatty liver disease), commonly occurring in individuals with obesity and type 2 diabetes can lead to liver inflammation/ fibrosis. MASLD results from fat being disproportionately deposited in the liver.
The goal of this mechanistic study is to investigate metabolic response in patients aged 20 to 80 years with non…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* aged 20 to 80 years;
* diagnosed with MASLD, defined as the presence of liver steatosis + abdominal obesity (as defined by the International Diabetes Federation country/ethnic group-specific criteria;
Exclusion Criteria:
1\) Presence of advanced fibrosis using any of the fol…
Contacts