Phase II Clinical Study of GemOX Hepatic Arterial Infusion Combined with Lenvatinib and Toripalimab for Advanced and Unresectable Intrahepatic Cholangiocarcinoma and Gallbladder Cancer

Recruiting Phase 2 Interventional Study
Intrahepatic Cholangiocarcinoma (Icc) Gall Bladder Cancer
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
33 (estimated)
Sponsor
Tianjin Medical University Cancer Institute and Hospital · Other
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About This Trial
For advanced unresectable intrahepatic cholangiocarcinoma and gallbladder cancer, the current standard first-line treatment is a combination of chemotherapy and immunotherapy. However, the efficacy rates remain low. Hepatic artery infusion chemotherapy can reduce systemic drug dosages while increasing local drug concentrations, which is expected to enhance overall efficacy and minimize drug toxici…
Trial Locations
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Eligibility Criteria
Inclusion Criteria 1. Age 18 or above 2. Histopathological or cytological diagnosis of intrahepatic cholangiocarcinoma or gallbladder cancer 3. A tumor that cannot be removed by three independent surgeons. 4. Expected lifespan ≥ 12 weeks 5. ECOG PS score 0-1 points 6. The patient voluntarily partic…
Contacts

Tianjin Medical University Cancer Institute and Hospital Department of Hepatobiliary Cancer

86-2223340123

zhang.wei@tmu.edu.cn

CONTACT

wei zhang, surgical chief physician, M.D., Ph.D.

8618622025401

zhang.wei@tmu.edu.cn

CONTACT