No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
25 and older
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
20 (estimated)
Sponsor
Columbia University · Other
Who this trial is looking for
This trial is looking for adults with obesity who are interested in understanding how different diets affect their body's energy use. Participants will follow one of two diets: one high in ultra-processed foods and one low in ultra-processed foods.
Are You a Good Fit for This Trial?
You may be able to join if
I have a BMI between 30 and 40
I am weight stable
I can download and use an app for the study
I do my own grocery shopping
I am otherwise healthy
You may not be able to join if
I am pregnant
I have had or plan to have bariatric surgery
I have a history of anti-obesity medications
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Ultra processed food is everywhere in modern society and may contain multiple ingredients that affect the way participants' bodies store energy. Some studies have shown that eating a diet high in ultra processed foods leads to weight gain, but these foods have not been studied enough to understand why. Recently, the gut microbiome has become a potential way to measure energy balance in the human b…
Ultra processed food is everywhere in modern society and may contain multiple ingredients that affect the way participants' bodies store energy. Some studies have shown that eating a diet high in ultra processed foods leads to weight gain, but these foods have not been studied enough to understand why. Recently, the gut microbiome has become a potential way to measure energy balance in the human body; this is done by measuring how many calories are in the stool. The investigators propose to test a very high ultra-processed food diet where 80% of calories are coming from ultra processed food and a low ultra processed food diet where 20% of the calories are coming from ultra processed food. This study will compare stool sample energy content of the two diets.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* BMI 30-40kg/m2
* weight stable
* able to download app and willing to use it for duration of study
* does own grocery shopping
* otherwise healthy
Exclusion Criteria:
* pregnancy
* history of or planned bariatric surgery
* history of anti obesity medications
Inclusion Criteria:
* BMI 30-40kg/m2
* weight stable
* able to download app and willing to use it for duration of study
* does own grocery shopping
* otherwise healthy
Exclusion Criteria:
* pregnancy
* history of or planned bariatric surgery
* history of anti obesity medications
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