Sodium Bicarbonate for Reducing Radiation-Induced Oral Mucositis in Nasopharyngeal Carcinoma.
Recruiting
Phase 2
Phase 3
Interventional Study
Nasopharyngeal Cancinoma (NPC)
Pivotal Trial
This treatment is in the last trial phase before FDA approval.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 – 70
- Sex
- Any
- Trial phase
- Phase 2/3
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 196 (estimated)
- Sponsor
- Sun Yat-sen University · Other
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About This Trial
To evaluate whether the use of 2.5% sodium bicarbonate mouthwash throughout the entire course of radiotherapy for nasopharyngeal carcinoma reduces the severity of radiation-induced oral mucositis and improves patient adherence to treatment.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Histopathologically confirmed nasopharyngeal carcinoma.
2. No evidence of distant metastasis (M0).
3. Scheduled to receive radical radiotherapy.
4. Karnofsky scale (KPS) \> 70.
5. Age 18-70 years.
6. Capacity for independent oral rinse administration without dysphagia.
Exclu…
Contacts