Deep Brain Stimulation for Parkinson's Disease Symptoms
Optimizing Deep Brain Stimulation to Improve Visuomotor Function in Parkinson's Disease
Recruiting
Observational Study
Parkinson's Disease
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Sex
- Any
- Study type
- Observational
- Participants needed
- 80 (estimated)
- Sponsor
- VA Office of Research and Development · Federal
Who this trial is looking for
This trial is looking for people with Parkinson's disease who have received deep brain stimulation (DBS) treatment. Participants will have their eye movement tracked to help improve treatments for their symptoms.
Are You a Good Fit for This Trial?
You may be able to join if
- I have Parkinson's disease and have received bilateral STN DBS
- I can provide pre-operative MRI images and can get post-operative scans
- I am in Hoehn and Yahr stage 2-4 when not taking medication
- I have a stable medication regimen for Parkinson's disease
- I have stable DBS parameter settings
You may not be able to join if
- I have had previous surgery for Parkinson's disease other than DBS
- I have dementia
- I have untreated depression or anxiety that is significant
- I have clinical signs that suggest atypical parkinsonism
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
Inability to align and refocus the eyes on the objects at different depths, i.e., vergence impairment and strabismus, frequently affects the quality of life in patients with Parkinson's disease. The investigators study aims to understand the location-specific effects of subthalamic region deep brain stimulation on vergence and strabismus by integrating the patient-specific deep brain stimulation m…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Parkinson's disease with bilateral STN DBS
* Availability of pre-operative MR images (with a T1-weighted, gradient-echo sequence) and ability to get post-operative MRI or CT scans
* Hoehn and Yahr stage 2-4 when off medication, and a stable antiparkinsonian medication regimen …
Contacts