Bariatric Surgery Effects on Brain Function

WISE-2B Brain Study (Weight Loss Intervention Surgical Effects on Brain Function)

Recruiting N/A Interventional Study
Diabetes Weight Loss
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
20 – 75
Sex
Any
Study type
Interventional
Purpose
Other
Participants needed
120 (estimated)
Sponsor
University of Florida · Other
Who this trial is looking for

This trial is looking for people aged 20 to 75 who are overweight and have diabetes. Participants will undergo bariatric surgery and possibly a small nerve stimulation treatment to see how it affects brain function.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am between 20 and 75 years old
  • I speak English
  • I can move around physically
  • I have a body mass index (BMI) over 35
  • I can have an MRI scan
  • I am willing to provide a small blood sample
  • I can give informed consent

You may not be able to join if

  • I have a current or past neurological disorder
  • I have a major psychiatric disturbance
  • I have unstable medical conditions like cancer
  • I cannot have an MRI due to claustrophobia or metal implants
  • My waist or torso circumference is too large

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial

The goal of the study to understand the effects of weight loss and improvements in diabetes following bariatric surgery on brain function and thinking. This study will also examine whether non-invasive transcutaneous vagal nerve stimulation (tVNS) intervention initiated 30 days post-surgery improves brain function and thinking. The study does NOT cover any costs associated with bariatric surgery.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Between age: 20-75 yrs, English speaking, Physically mobile * Body Mass Index (BMI) \>35 kg before surgery * Compatible of MRI Scanning * Willing to give a small blood sample * Capable of providing informed consent Exclusion Criteria: * Prior or current neurological disorder…
Contacts

Keyanni J Johnson

3522945618

kjjohnson@ufl.edu

CONTACT

Ronald Cohen, PhD

352-295-5840

roncohen@ufl.edu

CONTACT