Study of the Link Between MASH ( Metabolic Dysfunction-Associated Steatohepatitis) and MAMs (Mitochondria-Associated Membranes ) Alteration in Patients Undergoing Bariatric Surgery - MAMBA

Recruiting Observational Study
Metabolic Dysfunction-Associated Steatotic Liver Disease Metabolic Dysfunction-Associated Steatohepatitis Sleeve Gastrectomy Gastric Bypass Surgery
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 – 99
Sex
Any
Study type
Observational
Participants needed
20 (estimated)
Sponsor
Hospices Civils de Lyon · Other
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About This Trial
The main research hypothesis is that alterations in the communication between the endoplasmic reticulum (ER) and the mitochondria at contact sites called mitochondria-associated membranes (MAMs) occurs in different hepatic cell types of patients with Metabolic Dysfunction-Associated Steatotic Liver Disease (MALSD) and is involved in the progression towards MASH and could also influence the process…
Trial Locations
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Eligibility Criteria
* Inclusion Criteria \* : * Female or male adult patients * Patient who has benefited from a pluridisciplinary evaluation (medical, surgical, psychiatric), with a favorable opinion for a sleeve gastrectomy or a gastric bypass. * Patient with an indication Indication for intraoperative liver b…
Contacts

Cyrielle CAUSSY, Pr

+33 4 78 86 44 48

cyrielle.caussy@chu-lyon.fr

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