Low-Dose Radiotherapy for Knee Osteoarthritis

Radio- KO Radiotherapy for Knee Osteoarthritis Clinical Trial

Recruiting N/A Interventional Study
Osteoarthritis, Knee
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
50 – 100
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
128 (estimated)
Sponsor
Mayo Clinic · Other
Who this trial is looking for

This trial is looking for people aged 50 to 100 who have knee pain from osteoarthritis. Participants will receive low-dose radiotherapy to see if it helps reduce pain compared to a fake treatment.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am between 50 and 100 years old.
  • I have constant or intermittent pain in my knee.
  • I have been diagnosed with knee osteoarthritis.
  • I can complete electronic surveys.

You may not be able to join if

  • I am pregnant or can become pregnant without being sterilized.
  • I have had recent knee trauma that causes my pain.
  • I have inflammatory arthritis.
  • I have symptomatic hip osteoarthritis.
  • I have uncontrolled psychiatric illness.
  • I have had knee surgery on the same side before.
  • I had a corticosteroid injection in my knee within the last 3 months.
  • I regularly use opioids for pain.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

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About This Trial

The primary aim of this study is to investigate whether low-dose radiotherapy is an effective treatment to reduce the pain of knee osteoarthritis. A secondary aim is to determine whether patients experience any more measurable side effects than those receiving sham treatments.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: Age 50-100 years with a Mayo Clinic Rochester primary care provider At least moderate constant (ICOAP item A1) or intermittent (ICOAP item B6) pain Diagnosis of primary knee OA (ICD-10 M17.x) without recurrent acute inflammatory flares Joint-line tenderness on examination co-loc…
Contacts

Family Medicine Research Study Coordinators

507-422-6823

RSTFMSC@mayo.edu

CONTACT