No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 – 45
Sex
Female
Study type
Observational
Participants needed
120 (estimated)
Sponsor
Attikon Hospital · Other
Who this trial is looking for
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The aim of the present study is to investigate a) the presence of subclinical markers of vascular, myocardial and endothelial function in women with PCOS b) the acute alterations in these markers during the oral glucose tolerance test (OGTT) c) the impact of potential treatment interventions in these markers.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Age \> 16 years old
2. Diagonis of PCOS according to Rotterdam criteria: presence of two of the three of the following:
* Clinical or biochemical hyperandrogenism
* Anovulation or oligo-ovulation
* Polycystic ovarian morphology (PCOM)
3. Absence of treatment for PCO…
Inclusion Criteria:
1. Age \> 16 years old
2. Diagonis of PCOS according to Rotterdam criteria: presence of two of the three of the following:
* Clinical or biochemical hyperandrogenism
* Anovulation or oligo-ovulation
* Polycystic ovarian morphology (PCOM)
3. Absence of treatment for PCOS the last six months
4. Patients who have the ability to understand and sign the consent form.
Exclusion Criteria:
1. Disorders with clinical presentation similar to PCOS: thyroid disease, hyperprolactinemia, and non-classic congenital adrenal hyperplasia (primarily 21-hydroxylase deficiency by serum 17-hydroxyprogesterone \[17-OHP\]), Cushing syndrome, acromegaly
2. Treatment with contraceptive or metformin
3. Type 2 diabetes mellitus
4. Treatment for diabetes
5. Pregnancy
6. Lactation
7. Malignancy
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