Comparing Hydrocortisone and Prednisolone for Community Acquired Pneumonia (CAP)

Recruiting Phase 4 Interventional Study
Community Acquired Pneumonia (CAP)
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
1,600 (estimated)
Sponsor
Copenhagen Respiratory Research · Research network
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About This Trial
The goal of this cluster randomized controlled trial is to determine the optimal treatment for community aquired pneumonia (CAP). The study compares the effects and side effects of hydrocortisone and prednisolone in patients above 18 years old diagnosed with severe CAP. The main question is whether there is a difference in all cause mortality within thirty days. Participants will be randomized to…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age \> 18 years * Diagnosis of severe CAP for who the physician in charge decides for corticosteroid therapy for severe CAP. Exclusion Criteria: * Admitted \>24 h * Pregnant or breastfeeding women * Active tuberculosis or fungal infection * Pneumonia caused by influenza * In…
Contacts

Jens-Ulrik Stæhr Jensen, MD, PHD

38673057

jens.ulrik.jensen@regionh.dk

CONTACT

Pradeesh Sivapalan, MD, PHD

29880601

pradeesh.sivapalan.02@regionh.dk

CONTACT