Evaluation of Plasma Renin Concentrations in Cardiac Surgery
Recruiting
Observational Study
Cardiac Surgery With Cardiopulmonary Bypass
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
100 (estimated)
Sponsor
Mayo Clinic · Other
Who this trial is looking for
This trial is looking for adults who are scheduled for open heart surgery using a heart-lung machine. Participants will provide blood samples to help researchers understand how a certain protein in the blood changes during surgery.
Are You a Good Fit for This Trial?
You may be able to join if
I am 18 years old or older.
I am scheduled for elective cardiac surgery with cardiopulmonary bypass.
You may not be able to join if
I am having a heart or lung transplant.
I need emergency cardiac surgery.
I have been diagnosed with congenital heart disease.
I have end-stage kidney disease and receive kidney replacement therapy.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
The purpose of this research is to learn more about how renin (a blood test) is affected by cardiopulmonary bypass, the heart-lung machine used during open heart surgery. Renin is a protein that may be elevated in response to low blood pressure or situations where organs do not receive sufficient oxygen. Renin may potentially be used as an indicator for specific treatments aimed to increase the bl…
The purpose of this research is to learn more about how renin (a blood test) is affected by cardiopulmonary bypass, the heart-lung machine used during open heart surgery. Renin is a protein that may be elevated in response to low blood pressure or situations where organs do not receive sufficient oxygen. Renin may potentially be used as an indicator for specific treatments aimed to increase the blood pressure. This study will evaluate blood samples for renin concentration throughout the course of open heart surgery.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Adult persons 18 years of age or greater.
* Scheduled for an elective cardiac surgical procedure involving the use of cardiopulmonary bypass.
Exclusion Criteria:
* Surgery involving heart or lung transplantation or implant of a durable left ventricular assist device.
* Emerg…
Inclusion Criteria:
* Adult persons 18 years of age or greater.
* Scheduled for an elective cardiac surgical procedure involving the use of cardiopulmonary bypass.
Exclusion Criteria:
* Surgery involving heart or lung transplantation or implant of a durable left ventricular assist device.
* Emergency cardiac surgery.
* Established diagnosis of any congenital heart disease.
* End-stage kidney disease receiving kidney replacement therapy before surgery.
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