Evaluating Mechanically Engineered Stem Cell Exosomes for Treating Endometrial Injury: A Clinical Study
Recruiting
Phase 1
Phase 2
Interventional Study
Thin Endometrial Lining
Female Infertility
Intrauterine Adhesions
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 20 – 40
- Sex
- Female
- Trial phase
- Phase 1/2
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 90 (estimated)
- Sponsor
- Tang-Du Hospital · Other
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About This Trial
The goal of this clinical trial is to evaluate if engineered mechanically umbilical cord-derived stem cell exosomes, or conventional umbilical cord -derived stem cell exosomes, can improve endometrial thickness in women with thin endometrium.
The main questions it aims to answer are:
Can exosomes delivered via subendometrial injection improve endometrial thickness or clinical pregnancy rates com…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Females aged 20-40 years (inclusive of boundary values);
2. Normal ovarian reserve function (criteria: AFC ≥ 7, AMH \> 1.1 ng/mL);
3. History of transcervical resection of adhesions (TCRA);
4. Received PRP treatment after TCRA;
5. At least one embryo transfer (ET) cycle in wh…
Contacts