Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients
Recruiting
Phase 4
Interventional Study
Orthopedic Trauma Surgery Patients
Postoperative Pain
Opioid Use
Depression
Post-traumatic Stress Disorder (PTSD)
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 – 65
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 90 (estimated)
- Sponsor
- Texas Tech University Health Sciences Center · Other
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About This Trial
The goal of this clinical trial is to learn if ketamine, given during surgery, can help improve recovery for adults with serious orthopedic trauma. The study will test whether ketamine reduces pain, lowers the need for opioids, and improves mental health outcomes like depression and post-traumatic stress disorder (PTSD).
The main questions it aims to answer are:
Does ketamine reduce pain after s…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Adults aged 18-65
* Undergoing acute operative fixation for musculoskeletal trauma
* Injury Severity Score (ISS) greater than 15
* Ability to provide informed consent (or consent provided by a legally authorized representative)
Exclusion Criteria:
* Age under 18 or over 65
*…
Contacts