Ovarian-Sparing Adaptive Radiotherapy in Young Adult Women
Recruiting
Observational Study
Uterine Cancer
Rectal Cancer
Colon Cancer
Breast Cancer
Lung Cancer
Sarcoma
Cervix Cancer
Head and Neck Cancer
Anal Cancer
Liver Cancer
Gastric Cancer
Bladder Cancer
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 50
- Sex
- Female
- Study type
- Observational
- Participants needed
- 11 (estimated)
- Sponsor
- Washington University School of Medicine · Other
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About This Trial
Female patients with early onset (\<50 years old) pelvic malignancies such as uterine and rectal cancers are rising in incidence, which often requires pelvic radiation; many of these patients are premenopausal and at a high risk of premature ovarian failure from radiotherapy. Premature ovarian failure carries significant cardiac, musculoskeletal, sexual, and psychosocial morbidity. Ovarian transpo…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Biologic female
* Age between 18 and 50 years old (inclusive)
* Clinically premenopausal (defined as having active, regular menstruation without vasomotor symptoms)
* At least one of two ovaries readily visualized on diagnostic CT or MR imaging as confirmed by radiologist
* Pl…
Contacts