Lidocaine Versus Diphenhydramine to Achieve Local Anesthesia for Laceration Repairs
Recruiting
Phase 3
Interventional Study
Laceration of Skin
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Pivotal Trial
This treatment is in the last trial phase before FDA approval.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 3
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 100 (estimated)
- Sponsor
- Florida Atlantic University · Other
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About This Trial
Diphenhydramine, when injected locally, has been shown to achieve a certain level of local anesthesia. It has been documented for use in simple bedside procedures, however there is a gap in knowledge in its comparison to lidocaine. The purpose of the study is to determine if local infiltration of diphenhydramine is noninferior to the use of lidocaine 1% when trying to achieve local anesthesia for …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Lacerations requiring one layer of sutures
* Lacerations appropriate for repair by emergency physicians
Exclusion Criteria:
* Active bleeding from laceration
* Complex lacerations requiring multiple layers
* Lacerations to be repaired by a specialist service
* Patients with …
Contacts
No contact information available.