Long-Term Multidisciplinary Physiotherapy for Breast Cancer Survivors: A Randomized Controlled Trial

Inclusion Criteria: Women aged between 18 and 65 years. History of breast cancer surgery (with or without axillary lymph node dissection). Completed acute cancer treatment (surgery, chemotherapy, and/or radiation) at least 6 months prior to enrollment. Currently in the survivorship phase, with no active evidence of disease. Experiencing persistent sequelae related to treatment, such as: Moderate to severe pain (e.g., VAS score ≥ 30 on a 0-100 scale), and/or Upper limb dysfunction, and/or Cancer-related fatigue (as measured by FACIT-Fatigue). Able to understand and provide written informed consent. Exclusion Criteria: Diagnosis of recurrent or metastatic breast cancer. Currently receiving active cancer treatment (chemotherapy, radiation for active disease, or immunotherapy). Participation in another interventional trial targeting pain or rehabilitation within the past 3 months. Presence of severe comorbidities (e.g., uncontrolled cardiovascular disease, severe orthopedic or neurological conditions) that would preclude safe participation in physiotherapy. Any physical or psychological condition that, in the opinion of the investigator, would interfere with participation or adherence to the study protocol (e.g., severe cognitive impairment). Pregnancy or breastfeeding.