No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
15 – 40
Sex
Female
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
60 (estimated)
Sponsor
Memorial Sloan Kettering Cancer Center · Other
Who this trial is looking for
This trial is looking for women aged 15 to 40 who have lost their periods after chemotherapy for cancer. Participants will receive acupuncture and share how it affects their menstrual cycles and symptoms.
Are You a Good Fit for This Trial?
You may be able to join if
I am a woman between the ages of 15 and 40.
I have been diagnosed with stage I, II, or III cancer or a stable stage IV hematologic malignancy.
I completed chemotherapy within the past year.
I have regular menstrual periods at the time of my cancer diagnosis.
I have not had my period for at least 3 months since completing chemotherapy.
I am willing to follow all study procedures.
You may not be able to join if
I have been pregnant or breastfeeding in the last 3 months.
I have had a hysterectomy or both ovaries removed.
I am currently receiving radiation or planning surgery in the next 4 months.
I have used acupuncture for period recovery in the past 3 months.
I have been using ovarian suppression medicine or hormonal contraception in the past 3 months.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The purpose of this study is to find out whether it is practical (feasible) to use acupuncture to treat period loss (amenorrhea) caused by chemotherapy treatment in people with cancer. The researchers will look at how many participants enroll and complete the study. The researchers will also study how treatment with acupuncture affects the amount of time for the menstrual cycle to return and sympt…
The purpose of this study is to find out whether it is practical (feasible) to use acupuncture to treat period loss (amenorrhea) caused by chemotherapy treatment in people with cancer. The researchers will look at how many participants enroll and complete the study. The researchers will also study how treatment with acupuncture affects the amount of time for the menstrual cycle to return and symptoms and quality of life related to amenorrhea.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* English speaking woman between the ages of 15 and 40
* History of stage I, II, or III cancer OR stage IV or unstaged hematologic malignancy (e.g. lymphoma, leukemia, myeloma) that is stable, as assessed by care team
* Premenopausal status with regular menstruation at the time …
Inclusion Criteria:
* English speaking woman between the ages of 15 and 40
* History of stage I, II, or III cancer OR stage IV or unstaged hematologic malignancy (e.g. lymphoma, leukemia, myeloma) that is stable, as assessed by care team
* Premenopausal status with regular menstruation at the time of diagnosis by patient report
* Completed cytotoxic chemotherapy within the past year
* Premenopausal status with regular menstruation at the time of diagnosis by patient report for females ages 18 or older
* Report cessation of menses during or after chemotherapy and have not experienced menses recovery at the time of enrollment.
* Have reached menarche prior to therapy or during therapy for females between 15 and 17 years old
* Patient meets at least one of the following:
* Reports cessation of menses during or after chemotherapy and have not experienced menses recovery at the time of enrollment and has been without menses for at least 3 months 64 following the completion of cytotoxic chemotherapy; OR
* Is receiving ovarian suppression therapy (e.g., leuprolide \[Lupron\] or goserelin \[Zoladex\]) or hormonal contraceptive drugs, regardless of menstrual status, and report persistent (≥3 months), moderate-to- severe menopause-related symptoms, defined as a score of ≥4 on a 0-10 scale for at least one MENQOL item during eligibility screening.
* Willing to adhere to all study-related procedures, including randomization to one of the two possible arms: acupuncture and WLC
Exclusion Criteria:
* Had been pregnant or lactating within 3 months prior to enrollment
* History of hysterectomy or bilateral oophorectomy
* Ongoing or planned radiation or surgery within 4 months from randomization
* Use of acupuncture for menses recovery within 3 months of enrollment
* Had been or will be receiving ovarian suppression medicine, such as leuprolide (Lupron) and goserelin (Zoladex), or hormonal contraception drugs within 3 months of enrollment or during the study period
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