Renal Perfusion and the Development of AKI Following Traumatic Injury
Recruiting
Observational Study
Traumatic Haemorrhagic Shock
AKI (Acute Kidney Injury) Due to Trauma
AKI - Acute Kidney Injury
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 20 (estimated)
- Sponsor
- King's College Hospital NHS Trust · Other
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About This Trial
Acute kidney injury (AKI) is a complication of traumatic haemorrhagic shock (THS) and together these conditions increase mortality risk. Although septic shock patients who develop severe AKI are known to develop hypoperfusion of the renal cortex, little is known regarding intra-renal perfusion changes in THS. The aim of the current study is to investigate the effects of THS on renal microcirculato…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age \> 18 years
* Within 24 hours of ICU admission following traumatic injury
* Received any blood products during initial resuscitation
* Lactate \> 2 mmol/l at any stage prior to study enrolment
Exclusion Criteria:
* Known intolerance to Sonovue or any other ultrasound con…
Contacts